Submission Details

Molecule(s):
Oc1ccccc1CN1CCN(c2nc3ccccc3[nH]2)CC1

SWA-SYN-40d44a84-1

Oc1ccccc1CN1CCN(c2nc3ccccc3[nH]2)CC1

CS(=O)(=O)Nc1ccc2[nH]c(C(=O)N3CCN(C(=O)CCl)CC3)cc2c1

SWA-SYN-40d44a84-2

CS(=O)(=O)Nc1ccc2[nH]c(C(=O)N3CCN(C(=O)CCl)CC3)cc2c1

piperazine-chloroacetamide Check Availability on Manifold View
O=C(Nc1ccccc1)c1cccc2[nH]c(NCc3ccccc3O)nc12

SWA-SYN-40d44a84-3

O=C(Nc1ccccc1)c1cccc2[nH]c(NCc3ccccc3O)nc12

O=c1[nH]cccc1CNc1nc2ccccc2[nH]1

SWA-SYN-40d44a84-4

O=c1[nH]cccc1CNc1nc2ccccc2[nH]1

FC(F)c1ccccc1CNc1nc2ccccc2[nH]1

SWA-SYN-40d44a84-5

FC(F)c1ccccc1CNc1nc2ccccc2[nH]1


Design Rationale:

By eye and bioisosterism

Inspired By:
Discussion: