Submission Details

SEA-TRI-2dd971ce
Molecule(s):
C=CC(=O)CN(C(=O)Nc1cccc(Cl)c1)c1cncnc1

SEA-TRI-2dd971ce-1

C=CC(=O)CN(C(=O)Nc1cccc(Cl)c1)c1cncnc1

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Non-covalent -> covalent. Pyridine to pyrimidine to account for CyP450s Alternative cysteine reactive moiety.

Other Notes:

SMcK-004

Inspired By:
Discussion:

Contributor: Sean McKenna, Trinity College Dublin - Thu, 02 Apr 2020 08:06:56 +0000