Submission Details

SEA-TRI-146a67b6

Molecule(s):

C=C(Cc1ccon1)C(=O)N1CCN(Cc2cccc(Cl)c2)CC1

SEA-TRI-146a67b6-1

C=C(Cc1ccon1)C(=O)N1CCN(Cc2cccc(Cl)c2)CC1

Ordered Check Availability on Manifold View

Design Rationale:

Alternative cysteine reactive michael acceptor Shifted H-bond acceptor to a different position on the ring

Other Notes:

SMcK-016

Inspired By:

O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

MED-COV-4280ac29-15

Discussion:

Contributor: Sean McKenna, Trinity College Dublin - Thu, 02 Apr 2020 09:56:04 +0000