Submission Details

SAM-UNK-2684b532
Molecule(s):
Cc1ccncc1NC(=O)C(c1ccccc1)c1cccc(Cl)c1

SAM-UNK-2684b532-1

Cc1ccncc1NC(=O)C(c1ccccc1)c1cccc(Cl)c1

3-aminopyridine-like Check Availability on Manifold View
Cc1ccncc1NC(=O)N(c1ccccc1)c1cccc(Cl)c1

SAM-UNK-2684b532-2

Cc1ccncc1NC(=O)N(c1ccccc1)c1cccc(Cl)c1

3-aminopyridine-like Check Availability on Manifold View
Cc1nnc(C(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

SAM-UNK-2684b532-3
Duplicate of:
TRY-UNI-9f475305-3

Cc1nnc(C(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

Duplicate 3-aminopyridine-like Check Availability on Manifold View
Cc1nnc(N(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

SAM-UNK-2684b532-4

Cc1nnc(N(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

3-aminopyridine-like Check Availability on Manifold View
CC(C(=O)Nc1cnccc1C(F)F)c1cccc(Cl)c1

SAM-UNK-2684b532-5

CC(C(=O)Nc1cnccc1C(F)F)c1cccc(Cl)c1

3-aminopyridine-like Check Availability on Manifold View
CC(C(=O)Nc1cnccc1C(F)(F)F)c1cccc(Cl)c1

SAM-UNK-2684b532-6

CC(C(=O)Nc1cnccc1C(F)(F)F)c1cccc(Cl)c1

3-aminopyridine-like Check Availability on Manifold View
CC(C(=O)Nc1cnccc1Cl)c1cccc(Cl)c1

SAM-UNK-2684b532-7

CC(C(=O)Nc1cnccc1Cl)c1cccc(Cl)c1

3-aminopyridine-like Check Availability on Manifold View
Cc1ccncc1NC(=O)Nc1ccccc1CN1CCC(O)CC1

SAM-UNK-2684b532-8

Cc1ccncc1NC(=O)Nc1ccccc1CN1CCC(O)CC1

3-aminopyridine-like Check Availability on Manifold View
Cc1ccncc1NC(=O)Cc1ccccc1CN1CCC(O)CC1

SAM-UNK-2684b532-9

Cc1ccncc1NC(=O)Cc1ccccc1CN1CCC(O)CC1

3-aminopyridine-like Check Availability on Manifold View
Cc1ccncc1NC(=O)C(CN1CCC(O)CC1)c1ccccc1

SAM-UNK-2684b532-10

Cc1ccncc1NC(=O)C(CN1CCC(O)CC1)c1ccccc1

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(F)F

SAM-UNK-2684b532-11

O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(F)F

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(F)(F)F

SAM-UNK-2684b532-12

O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(F)(F)F

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1Cl

SAM-UNK-2684b532-13
Duplicate of:
ALP-POS-95b75b4d-8

O=C(Cc1cccc(Cl)c1)Nc1cnccc1Cl

Duplicate 3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)N1CCc2ccncc21

SAM-UNK-2684b532-14

O=C(Cc1cccc(Cl)c1)N1CCc2ccncc21

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Some simple fragment merges of X_0434, X_0387 & X_0395 and a few 4-methylpyridine analogues reaching towards Asn142

Inspired By:
Discussion:

Contributor: Sam - Thu, 28 May 2020 22:22:44 +0000