Submission Details

RUB-POS-1325a9ea
Molecule(s):
O=C(Cc1cccc(Cl)c1)Nc1cncc2c1CC(=O)N2

RUB-POS-1325a9ea-1
Duplicate of:
MAT-POS-f7918075-7

O=C(Cc1cccc(Cl)c1)Nc1cncc2c1CC(=O)N2

Duplicate 3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2cccc(F)c12

RUB-POS-1325a9ea-2
Duplicate of:
MIC-UNK-50cce87d-1

O=C(Cc1cccc(Cl)c1)Nc1cncc2cccc(F)c12

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1cccc2cncc(NC(=O)Cc3cccc(Cl)c3)c12

RUB-POS-1325a9ea-3
Duplicate of:
MIC-UNK-50cce87d-3

Cc1cccc2cncc(NC(=O)Cc3cccc(Cl)c3)c12

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1ccc2cncc(NC(=O)Cc3cccc(Cl)c3)c2c1

RUB-POS-1325a9ea-4

Cc1ccc2cncc(NC(=O)Cc3cccc(Cl)c3)c2c1

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1cccc2c(NC(=O)Cc3cccc(Cl)c3)cncc12

RUB-POS-1325a9ea-5

Cc1cccc2c(NC(=O)Cc3cccc(Cl)c3)cncc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)NC1CNCc2ccccc21

RUB-POS-1325a9ea-6

O=C(Cc1cccc(Cl)c1)NC1CNCc2ccccc21

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)NC1C(=O)NCc2ccccc21

RUB-POS-1325a9ea-7

O=C(Cc1cccc(Cl)c1)NC1C(=O)NCc2ccccc21

O=C(Cc1cccc(Cl)c1)Nc1cncn2ccnc12

RUB-POS-1325a9ea-8

O=C(Cc1cccc(Cl)c1)Nc1cncn2ccnc12

3-aminopyridine-like Ordered Check Availability on Manifold View
COc1cccc2cncc(NC(=O)Cc3cccc(Cl)c3)c12

RUB-POS-1325a9ea-9
Duplicate of:
MIC-UNK-50cce87d-4

COc1cccc2cncc(NC(=O)Cc3cccc(Cl)c3)c12

Duplicate 3-aminopyridine-like Ordered Check Availability on Manifold View
COc1cc2cncc(NC(=O)C3CCOc4ccc(Cl)cc43)c2cc1OC

RUB-POS-1325a9ea-10

COc1cc2cncc(NC(=O)C3CCOc4ccc(Cl)cc43)c2cc1OC

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2ncoc12

RUB-POS-1325a9ea-11

O=C(Cc1cccc(Cl)c1)Nc1cncc2ncoc12

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2cn[nH]c12

RUB-POS-1325a9ea-12

O=C(Cc1cccc(Cl)c1)Nc1cncc2cn[nH]c12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2[nH]ncc12

RUB-POS-1325a9ea-13

O=C(Cc1cccc(Cl)c1)Nc1cncc2[nH]ncc12

3-aminopyridine-like Assayed Check Availability on Manifold View
Cn1ncc2cncc(NC(=O)Cc3cccc(Cl)c3)c21

RUB-POS-1325a9ea-14

Cn1ncc2cncc(NC(=O)Cc3cccc(Cl)c3)c21

3-aminopyridine-like Assayed Check Availability on Manifold View
Cn1ncc2c(NC(=O)Cc3cccc(Cl)c3)cncc21

RUB-POS-1325a9ea-15

Cn1ncc2c(NC(=O)Cc3cccc(Cl)c3)cncc21

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)NC1CC(=O)c2ccccc21

RUB-POS-1325a9ea-16
Duplicate of:
ALP-POS-8b8a49e1-6

O=C(Cc1cccc(Cl)c1)NC1CC(=O)c2ccccc21

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cnc(F)c2ccccc12

RUB-POS-1325a9ea-17

O=C(Cc1cccc(Cl)c1)Nc1cnc(F)c2ccccc12

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1c(F)ncc2ccccc12

RUB-POS-1325a9ea-18

O=C(Cc1cccc(Cl)c1)Nc1c(F)ncc2ccccc12

3-aminopyridine-like Ordered Check Availability on Manifold View
CC(C)(C)c1ccncc1NC(=O)Cc1cccc(Cl)c1

RUB-POS-1325a9ea-19

CC(C)(C)c1ccncc1NC(=O)Cc1cccc(Cl)c1

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)NC1COCc2ccccc21

RUB-POS-1325a9ea-20

O=C(Cc1cccc(Cl)c1)NC1COCc2ccccc21

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)NC1CS(=O)(=O)Cc2ccccc21

RUB-POS-1325a9ea-21

O=C(Cc1cccc(Cl)c1)NC1CS(=O)(=O)Cc2ccccc21

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)NC1=NC(=O)c2ccccc21

RUB-POS-1325a9ea-22

O=C(Cc1cccc(Cl)c1)NC1=NC(=O)c2ccccc21

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)NC1C(=O)Nc2ccccc21

RUB-POS-1325a9ea-23
Duplicate of:
VLA-UCB-1dbca3b4-1

O=C(Cc1cccc(Cl)c1)NC1C(=O)Nc2ccccc21

Duplicate Ugi Assayed Check Availability on Manifold View
CC1(C)Nc2ccccc2C1NC(=O)Cc1cccc(Cl)c1

RUB-POS-1325a9ea-24

CC1(C)Nc2ccccc2C1NC(=O)Cc1cccc(Cl)c1

3-aminopyridine-like Assayed Check Availability on Manifold View
Design Rationale:

Easy to make library probing potential isoquinoline replacements. Replacements partially mined from the literature, and based on purchasable building blocks.

Inspired By:
Discussion:

Contributor: Ruby Pai, PostEra - Sun, 07 Mar 2021 23:17:04 +0000