Submission Details

Molecule(s):
NS(=O)(=O)c1ccc2cccc(Cn3cc(-c4cccnc4)c(NC(=O)CCl)nc3=O)c2c1

NIM-UNI-7ba87d62-1

NS(=O)(=O)c1ccc2cccc(Cn3cc(-c4cccnc4)c(NC(=O)CCl)nc3=O)c2c1

Cc1ccccc1Cn1cc(-c2cccnc2)c(NC(=O)CCl)nc1=O

NIM-UNI-7ba87d62-2

Cc1ccccc1Cn1cc(-c2cccnc2)c(NC(=O)CCl)nc1=O

O=C(CCl)Nc1nc(=O)n(Cc2ccccc2Cl)cc1-c1cccnc1

NIM-UNI-7ba87d62-3

O=C(CCl)Nc1nc(=O)n(Cc2ccccc2Cl)cc1-c1cccnc1

O=C(CCl)Nc1nc(=O)n(Cc2ccsc2)cc1-c1cccnc1

NIM-UNI-7ba87d62-4

O=C(CCl)Nc1nc(=O)n(Cc2ccsc2)cc1-c1cccnc1

O=C(CCl)Nc1nc(=O)n(Cc2ccc(Br)s2)cc1-c1cccnc1

NIM-UNI-7ba87d62-5

O=C(CCl)Nc1nc(=O)n(Cc2ccc(Br)s2)cc1-c1cccnc1


Design Rationale:

Cytosine core to merge fragments

Other Notes:

Fragalysis snapshot https://fragalysis.diamond.ac.uk/viewer/react/snapshot/33e8072d-50cb-410d-825f-1ea1dc27bea8

Inspired By:
Discussion: