Submission Details

NAU-LAT-30527ac5
Molecule(s):
O=C(Cc1cc(Cl)cc2cc[nH]c12)Nc1cncc2ccccc12

NAU-LAT-30527ac5-1

O=C(Cc1cc(Cl)cc2cc[nH]c12)Nc1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc2cc[nH]c12

NAU-LAT-30527ac5-2

Cc1ccncc1NC(=O)Cc1cc(Cl)cc2cc[nH]c12

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cc(Cl)cc2cc[nH]c12)Nc1cc(=O)[nH]c2ccccc12

NAU-LAT-30527ac5-3

O=C(Cc1cc(Cl)cc2cc[nH]c12)Nc1cc(=O)[nH]c2ccccc12

3-aminopyridine-like Check Availability on Manifold View
CC(=O)NCCc1c[nH]c2c(CC(=O)Nc3cncc4ccccc34)cc(Cl)cc12

NAU-LAT-30527ac5-4

CC(=O)NCCc1c[nH]c2c(CC(=O)Nc3cncc4ccccc34)cc(Cl)cc12

3-aminopyridine-like Check Availability on Manifold View
CC(=O)NCCc1c[nH]c2c(CC(=O)Nc3cnccc3C)cc(Cl)cc12

NAU-LAT-30527ac5-5
Duplicate of:
NAU-LAT-0543f7f2-3

CC(=O)NCCc1c[nH]c2c(CC(=O)Nc3cnccc3C)cc(Cl)cc12

Duplicate 3-aminopyridine-like Check Availability on Manifold View
CC(=O)NCCc1c[nH]c2c(CC(=O)Nc3cc(=O)[nH]c4ccccc34)cc(Cl)cc12

NAU-LAT-30527ac5-6

CC(=O)NCCc1c[nH]c2c(CC(=O)Nc3cc(=O)[nH]c4ccccc34)cc(Cl)cc12

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Combining multiple hits with covalent inhibitor DUN-NEW-f8ce3686-24.

Inspired By:
Discussion:

Contributor: Nauris Narvaiss, Latvian Institute of Organic Synthesis - Wed, 11 Nov 2020 23:20:59 +0000