Submission Details

MIC-UNK-644c43c7
Molecule(s):
O=C(Cc1cc(Cl)cc(CCNCC(F)(F)F)c1)Nc1cncc2ccccc12

MIC-UNK-644c43c7-1

O=C(Cc1cc(Cl)cc(CCNCC(F)(F)F)c1)Nc1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cc(Cl)cc(CCNC(C(F)(F)F)C(F)(F)F)c1)Nc1cncc2ccccc12

MIC-UNK-644c43c7-2

O=C(Cc1cc(Cl)cc(CCNC(C(F)(F)F)C(F)(F)F)c1)Nc1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cc(Cl)cc(CNCC(F)(F)F)c1)Nc1cncc2ccccc12

MIC-UNK-644c43c7-3

O=C(Cc1cc(Cl)cc(CNCC(F)(F)F)c1)Nc1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cc(Cl)cc(CNC(C(F)(F)F)C(F)(F)F)c1)Nc1cncc2ccccc12

MIC-UNK-644c43c7-4

O=C(Cc1cc(Cl)cc(CNC(C(F)(F)F)C(F)(F)F)c1)Nc1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Same general idea as in PET-UNK-c5865d42-2 but without azetidine ring. Alternatively it can be seen as a highly fluorinated isostere of acetamide part of AAR-POS-d2a4d1df-2

Inspired By:
Discussion:

Contributor: Michal K - Thu, 24 Sep 2020 20:31:25 +0000