Submission Details

MIC-UNK-460e637d
Molecule(s):
CN1CCN(C(=O)Cc2cncc3ccccc23)CC1CNS(N)(=O)=O

MIC-UNK-460e637d-1

CN1CCN(C(=O)Cc2cncc3ccccc23)CC1CNS(N)(=O)=O

CN1CCN(C(=O)Cc2cncc3ccccc23)CC1COC1CC(=O)N1

MIC-UNK-460e637d-2

CN1CCN(C(=O)Cc2cncc3ccccc23)CC1COC1CC(=O)N1

CN1CCN(C(=O)Cc2cncc3ccccc23)CC1COc1cccnc1

MIC-UNK-460e637d-3

CN1CCN(C(=O)Cc2cncc3ccccc23)CC1COc1cccnc1

Design Rationale:

Some attempts to fill out beta-lactam pocket. This only will make sense if either AAR-POS-d2a4d1df-20 or something like MIC-UNK-a28eba03-2 turns out to be potent

Inspired By:
Discussion:

Contributor: Michal K - Thu, 03 Dec 2020 13:56:12 +0000