Submission Details

MAT-POS-54c4bf04
Molecule(s):
O=C(NCC1COc2ccccc2O1)c1cc(=O)[nH]c2ccccc12

MAT-POS-54c4bf04-1

O=C(NCC1COc2ccccc2O1)c1cc(=O)[nH]c2ccccc12

COc1ccc(Cl)cc1OCCNC(=O)c1cncc2ccccc12

MAT-POS-54c4bf04-2

COc1ccc(Cl)cc1OCCNC(=O)c1cncc2ccccc12

O=C(c1cncc2ccccc12)N1CCN(c2cccc(Cl)c2)CC1

MAT-POS-54c4bf04-3

O=C(c1cncc2ccccc12)N1CCN(c2cccc(Cl)c2)CC1

CC1CN(C(=O)c2cc(=O)[nH]c3ccccc23)CCN1c1cccc(Cl)c1

MAT-POS-54c4bf04-4

CC1CN(C(=O)c2cc(=O)[nH]c3ccccc23)CCN1c1cccc(Cl)c1

Design Rationale:

Simple explorations of quinolone structures trying to pick up some potency, building off ideas in ERI-UCB-d6de1f3c

Discussion:

Contributor: Matt Robinson, PostEra - Sun, 08 Nov 2020 03:11:30 +0000