Submission Details

Molecule(s):
CCS(=O)(=O)Nc1ccc2cncc(NC(=O)C3CCOc4ccc(Cl)cc43)c2c1

MAT-POS-419aafdb-1

CCS(=O)(=O)Nc1ccc2cncc(NC(=O)C3CCOc4ccc(Cl)cc43)c2c1

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccc(NS(=O)(=O)C3CC3)cc12)C1CCOc2ccc(Cl)cc21

MAT-POS-419aafdb-2

O=C(Nc1cncc2ccc(NS(=O)(=O)C3CC3)cc12)C1CCOc2ccc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View

Design Rationale:

Additional analogs to improve metabolism

Discussion: