Submission Details

MAT-POS-29385cc1
Molecule(s):
COc1cc2c(NC(=O)Cc3cccc(Cl)c3)cncc2cc1F

MAT-POS-29385cc1-1
Duplicate of:
PET-UNK-b38839dc-1

COc1cc2c(NC(=O)Cc3cccc(Cl)c3)cncc2cc1F

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
COc1cc2cncc(NC(=O)Cc3cccc(Cl)c3)c2cc1F

MAT-POS-29385cc1-2

COc1cc2cncc(NC(=O)Cc3cccc(Cl)c3)c2cc1F

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1ccc2c(NC(=O)Cc3cccc(Cl)c3)cncc2c1

MAT-POS-29385cc1-3

Cc1ccc2c(NC(=O)Cc3cccc(Cl)c3)cncc2c1

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1cc(F)cc2cncc(NC(=O)Cc3cccc(Cl)c3)c12

MAT-POS-29385cc1-4

Cc1cc(F)cc2cncc(NC(=O)Cc3cccc(Cl)c3)c12

3-aminopyridine-like Assayed Check Availability on Manifold View
Design Rationale:

Isoquinoline replacements attempting to balance potency and metabolic stability

Discussion:

Contributor: Matt Robinson, PostEra - Sun, 11 Jul 2021 22:28:05 +0000