Submission Details

MAK-UNK-3e0761f8
Molecule(s):
CC(=O)c1ccc(NC(=O)C2CC3CC2CN3C(=O)CCl)cc1

MAK-UNK-3e0761f8-1

CC(=O)c1ccc(NC(=O)C2CC3CC2CN3C(=O)CCl)cc1

Cc1nnc(C2C3CC(c4ccccc43)N2C(=O)CCl)o1

MAK-UNK-3e0761f8-2

Cc1nnc(C2C3CC(c4ccccc43)N2C(=O)CCl)o1

Cc1n[nH]c(-c2ccc(C)c(NC(=O)C3CC4CC3CN4C(=O)CCl)c2)n1

MAK-UNK-3e0761f8-3

Cc1n[nH]c(-c2ccc(C)c(NC(=O)C3CC4CC3CN4C(=O)CCl)c2)n1

Cc1cccc(C(CNS(C)(=O)=O)N2CC3CC2CN3C(=O)CCl)c1

MAK-UNK-3e0761f8-4

Cc1cccc(C(CNS(C)(=O)=O)N2CC3CC2CN3C(=O)CCl)c1

piperazine-chloroacetamide Check Availability on Manifold View
Cc1ccnc(NC(=O)C2CC3CC2CN3C(=O)CCl)c1

MAK-UNK-3e0761f8-5

Cc1ccnc(NC(=O)C2CC3CC2CN3C(=O)CCl)c1

Cc1ccnc2[nH]c(CC3CC4CC3CN4C(=O)CCl)nc12

MAK-UNK-3e0761f8-6

Cc1ccnc2[nH]c(CC3CC4CC3CN4C(=O)CCl)nc12

CCCc1n[nH]c(C2CN(C(=O)C3CC4CC3CN4C(=O)CCl)CCO2)n1

MAK-UNK-3e0761f8-7

CCCc1n[nH]c(C2CN(C(=O)C3CC4CC3CN4C(=O)CCl)CCO2)n1

CN(C(=O)C1CC2CC1CN2C(=O)CCl)c1ccccc1

MAK-UNK-3e0761f8-8

CN(C(=O)C1CC2CC1CN2C(=O)CCl)c1ccccc1

CN1CCC(C(c2ccccc2)N2CC3CC2CN3C(=O)CCl)CC1

MAK-UNK-3e0761f8-9

CN1CCC(C(c2ccccc2)N2CC3CC2CN3C(=O)CCl)CC1

piperazine-chloroacetamide Check Availability on Manifold View
CNC(=O)c1cc2cccc(CN3CC4CC3CN4C(=O)CCl)c2nc1N1CCOCC1

MAK-UNK-3e0761f8-10

CNC(=O)c1cc2cccc(CN3CC4CC3CN4C(=O)CCl)c2nc1N1CCOCC1

piperazine-chloroacetamide Check Availability on Manifold View
Design Rationale:

ordered chloroacetamides modified by adding an extra C atom above a piperidine or piperazine ring (similar to x0770 transformed into x3077)

Inspired By:
Discussion:

Contributor: Maksym Voznyy - Tue, 02 Jun 2020 00:44:39 +0000