Submission Details

LUO-POS-433ce175

Molecule(s):

CC1(C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2CNS1(=O)=O

LUO-POS-433ce175-1

CC1(C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2CNS1(=O)=O

3-aminopyridine-like Check Availability on Manifold View

Design Rationale:

Retain NH for expansion to solvent exposure side, hope to retain/improve potency while improve PK.

Inspired By:

CC1(C(=O)Nc2cncc3ccccc23)CNS(=O)(=O)c2ccc(Cl)cc21

ALP-POS-1cbc2fae-1

Discussion:

Contributor: Luong, PostEra - Tue, 19 Oct 2021 04:18:22 +0000