Submission Details

Molecule(s):

Design Rationale:

This molecule (Aurothioglucose) has the Catalog number HY-A0068 in the MedChemExpress Covalent Screening Library Plus. Given the results for other Gold complexes with our target it would be interesting to know if this molecules also binds.

Other Notes:

Obviously, a series based on this molecule has significant potential for additional binding away from CYS(145).

Discussion: