Submission Details
Molecule(s):
Nc1cncc(OC(=O)c2cccc(N)c2)c1
Cc1cccc(C(=O)Oc2cncc(F)c2)c1
O=C(Oc1cncc(F)c1)c1cccc2[nH]ccc12
O=C(Oc1cncc(F)c1)c1cccc(OBr)c1
NC(N)c1cccc(C(=O)Oc2cncc(F)c2)c1
N=C(N)c1cncc(OC(=O)c2cccc3[nH]ccc23)c1
NC(=O)c1ccc2[nH]ccc2c1C(=O)Oc1cncc(F)c1
O=C(Oc1cncc(F)c1)c1cncc(P)c1
Design Rationale:
Functional variations on old SARS inhibitors, through use of a quality-diversity algorithm.
Other Notes:
In collaboration with Jeriek Van den Abeele.