Submission Details

Molecule(s):
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O

JOH-MSK-8ad0fd05-1

CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H](C=O)C[C@@H]1CCNC1=O


Design Rationale:

GC373: feline coronavirus inhibitor claimed to also have activity against SARS-CoV-2 Mpro, after decomposition of GC376 prodrug

Other Notes:

See https://www.nature.com/articles/s41467-020-18096-2

Discussion: