Submission Details
Molecule(s):
CCCc1ccc(OCC(=O)N2CCN(C)CC2)cc1
Cc1ccc(OCC(=O)N2CCN([C@H](C)CNCCCO)CC2)cc1
C[C@@H](CC(=O)N1CCN(C)CC1)OCC1CCCCC1
Cc1ccc(OCC(=O)N2CCN(CN3C[C@@H](CO)OC[C@@H]3C)CC2)cc1
C[C@H](CS[C@H]1CCO[C@@H]1C)C(=O)N1CCN(C)CC1
Cc1ccc(OCC(=O)N2CCN([C@H](C)CSC3CCCC3)CC2)cc1
C[C@H](OCC1CCCCC1)C(=O)N1CCN(C)CC1
Cc1ccc(OCC(=O)N2CCN([C@@]3(CCC(C)C)CCCOC3)CC2)cc1
Cc1ccc(CSC(C)C)cc1
Design Rationale:
docking with SeeSAR - derivatives designed from starting with fragment