Submission Details

JOE-NOR-ee0d220f
Molecule(s):
O=C1C(=O)N(Cc2ncon2)c2ccc(S(=O)(=O)N3CCCC3)cc21

JOE-NOR-ee0d220f-1

O=C1C(=O)N(Cc2ncon2)c2ccc(S(=O)(=O)N3CCCC3)cc21

Design Rationale:

Add a pyrroldine sulfonamide to fill the P2 pocket of LOR-NOR-30067bb9-18. Design by isatin literature SAR and docking with Schrodinger software. PDB file of docking model provided

Inspired By:
Download PDB File
Discussion:

Contributor: Joe Eyermann, Northeastern University - Sun, 13 Sep 2020 19:13:47 +0000