Submission Details

JIN-POS-6dc588a4
Molecule(s):
O=C(Cn1cnc2ccccc21)Nc1cccc(Cl)c1

JIN-POS-6dc588a4-1
Duplicate of:
BEN-DND-61647d40-13

O=C(Cn1cnc2ccccc21)Nc1cccc(Cl)c1

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1noc2ncccc12

JIN-POS-6dc588a4-2

O=C(Cc1cccc(Cl)c1)Nc1noc2ncccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
COc1ccncc1NC(=O)Cc1cccc(Cl)c1

JIN-POS-6dc588a4-3

COc1ccncc1NC(=O)Cc1cccc(Cl)c1

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(F)(F)F

JIN-POS-6dc588a4-4
Duplicate of:
SAM-UNK-2684b532-12

O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(F)(F)F

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1c[nH]c2ccccc12

JIN-POS-6dc588a4-5

O=C(Cc1cccc(Cl)c1)Nc1c[nH]c2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
CC(C)(C)Oc1ccncc1NC(=O)Cc1cccc(Cl)c1

JIN-POS-6dc588a4-6

CC(C)(C)Oc1ccncc1NC(=O)Cc1cccc(Cl)c1

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1ncnc2ccccc12

JIN-POS-6dc588a4-7

O=C(Cc1cccc(Cl)c1)Nc1ncnc2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1noc2ccccc12

JIN-POS-6dc588a4-8

O=C(Cc1cccc(Cl)c1)Nc1noc2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cnn2ccccc12

JIN-POS-6dc588a4-9

O=C(Cc1cccc(Cl)c1)Nc1cnn2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2nccnc12

JIN-POS-6dc588a4-10

O=C(Cc1cccc(Cl)c1)Nc1cncc2nccnc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2cc(F)ccc12

JIN-POS-6dc588a4-11

O=C(Cc1cccc(Cl)c1)Nc1cncc2cc(F)ccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2[nH]ccc12

JIN-POS-6dc588a4-12

O=C(Cc1cccc(Cl)c1)Nc1cncc2[nH]ccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2c(F)cccc12

JIN-POS-6dc588a4-13

O=C(Cc1cccc(Cl)c1)Nc1cncc2c(F)cccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2cc[nH]c12

JIN-POS-6dc588a4-14

O=C(Cc1cccc(Cl)c1)Nc1cncc2cc[nH]c12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1noc2cccnc12

JIN-POS-6dc588a4-15

O=C(Cc1cccc(Cl)c1)Nc1noc2cccnc12

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1noc2cnccc12

JIN-POS-6dc588a4-16

O=C(Cc1cccc(Cl)c1)Nc1noc2cnccc12

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cc2nccn2cn1

JIN-POS-6dc588a4-17

O=C(Cc1cccc(Cl)c1)Nc1cc2nccn2cn1

3-aminopyridine-like Ordered Check Availability on Manifold View
COc1cccc2c(NC(=O)Cc3cccc(Cl)c3)cncc12

JIN-POS-6dc588a4-18

COc1cccc2c(NC(=O)Cc3cccc(Cl)c3)cncc12

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1c[nH]c(=O)c2ccccc12

JIN-POS-6dc588a4-19
Duplicate of:
MAT-POS-bb423b95-6

O=C(Cc1cccc(Cl)c1)Nc1c[nH]c(=O)c2ccccc12

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2c1NCCC2

JIN-POS-6dc588a4-20

O=C(Cc1cccc(Cl)c1)Nc1cncc2c1NCCC2

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1c(O)cnc2ccccc12

JIN-POS-6dc588a4-21

O=C(Cc1cccc(Cl)c1)Nc1c(O)cnc2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2sccc12

JIN-POS-6dc588a4-22

O=C(Cc1cccc(Cl)c1)Nc1cncc2sccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
COc1ncc(NC(=O)Cc2cccc(Cl)c2)c2ccccc12

JIN-POS-6dc588a4-23

COc1ncc(NC(=O)Cc2cccc(Cl)c2)c2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
N#Cc1ncc(NC(=O)Cc2cccc(Cl)c2)c2ccccc12

JIN-POS-6dc588a4-24

N#Cc1ncc(NC(=O)Cc2cccc(Cl)c2)c2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
Design Rationale:

Easy to make library probing potential isoquinoline replacements. Replacements partially mined from the literature, and based on purchasable building blocks.

Inspired By:
Discussion:

Contributor: Jin Pan, PostEra - Sun, 07 Mar 2021 23:10:16 +0000