Submission Details

Molecule(s):
O=C(CCl)N1CCCC(c2nc3ccccc3o2)C1

IND-SYN-6c8299e8-1

O=C(CCl)N1CCCC(c2nc3ccccc3o2)C1

O=C(CCl)N1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1

IND-SYN-6c8299e8-2

O=C(CCl)N1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1

piperazine-chloroacetamide Check Availability on Manifold View
O=C(CCl)N1Cc2ccccc2C(c2nc3ccccc3s2)C1

IND-SYN-6c8299e8-3

O=C(CCl)N1Cc2ccccc2C(c2nc3ccccc3s2)C1

CN1CCN(C(=O)Cc2n[nH]c3ncccc23)CC1

IND-SYN-6c8299e8-4

CN1CCN(C(=O)Cc2n[nH]c3ncccc23)CC1

O=C(Cc1c[nH]c2ncccc12)N1CCS(=O)(=O)CC1

IND-SYN-6c8299e8-5

O=C(Cc1c[nH]c2ncccc12)N1CCS(=O)(=O)CC1

O=C(Cn1cccn1)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

IND-SYN-6c8299e8-7

O=C(Cn1cccn1)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

O=C(CCl)Nc1cccc(N2CCCS2(=O)=O)c1

IND-SYN-6c8299e8-8
Duplicate of:
SWA-SYN-d2e6fa14-10

O=C(CCl)Nc1cccc(N2CCCS2(=O)=O)c1

O=C(CCl)Nc1cccc(S(=O)(=O)N2CCSCC2)c1

IND-SYN-6c8299e8-9

O=C(CCl)Nc1cccc(S(=O)(=O)N2CCSCC2)c1

CS(=O)(=O)Nc1ccc(Oc2ncccc2C#N)cc1

IND-SYN-6c8299e8-11

CS(=O)(=O)Nc1ccc(Oc2ncccc2C#N)cc1

O=C(Cn1cccn1)N1CCOC(c2ccc(F)cc2)C1

IND-SYN-6c8299e8-12

O=C(Cn1cccn1)N1CCOC(c2ccc(F)cc2)C1


Design Rationale:

bioisostere and by eye

Inspired By:
Discussion: