Submission Details

GIA-UNK-c4371e97
Molecule(s):
O=C(CCl)N1CC2CCC(C1)N2C(c1ccccc1)c1cc(Cl)cc(Cl)c1

GIA-UNK-c4371e97-1

O=C(CCl)N1CC2CCC(C1)N2C(c1ccccc1)c1cc(Cl)cc(Cl)c1

piperazine-chloroacetamide Check Availability on Manifold View
O=C(CCl)N1CC2CCC(C1)N2C(c1ccccc1)c1ccccc1

GIA-UNK-c4371e97-2

O=C(CCl)N1CC2CCC(C1)N2C(c1ccccc1)c1ccccc1

piperazine-chloroacetamide Check Availability on Manifold View
O=C(CCl)N1CC2CCC(C1)N2C(c1ccccc1)c1cccc(Cl)c1

GIA-UNK-c4371e97-3

O=C(CCl)N1CC2CCC(C1)N2C(c1ccccc1)c1cccc(Cl)c1

piperazine-chloroacetamide Check Availability on Manifold View
Design Rationale:

Introduction of bridged piperazine, in order to improve conformation of already observed good activity of piperazine biaryl derivatives.

Discussion:

Contributor: Gianfranco Lopopolo - Wed, 01 Jul 2020 18:10:10 +0000