Submission Details

Molecule(s):
Clc1ccc2c(c1)C1(CCO2)CCN(c2cncc3cccc(Cl)c23)C1

EDJ-MED-e78d5f1a-1

Clc1ccc2c(c1)C1(CCO2)CCN(c2cncc3cccc(Cl)c23)C1


Design Rationale:

Use 5-Cl isoquinoline to push pyrollidine out of plane

Discussion: