Submission Details

EDJ-MED-c5ca5386
Molecule(s):
O=C(Cc1cccc(Cl)c1)Nc1cncc2cc(F)cc(Cl)c12

EDJ-MED-c5ca5386-1

O=C(Cc1cccc(Cl)c1)Nc1cncc2cc(F)cc(Cl)c12

3-aminopyridine-like Assayed Check Availability on Manifold View
CS(=O)(=O)c1cc(Cl)c2c(NC(=O)Cc3cccc(Cl)c3)cncc2c1

EDJ-MED-c5ca5386-2

CS(=O)(=O)c1cc(Cl)c2c(NC(=O)Cc3cccc(Cl)c3)cncc2c1

3-aminopyridine-like Ordered Check Availability on Manifold View
Design Rationale:

Capitalise on 5-Cl improvements in potency to see if 5-Cl, 7X improves potency and metabolism.

Discussion:

Contributor: Ed J Griffen, MedChemica Ltd - Fri, 17 Sep 2021 16:53:56 +0000