Submission Details

EDJ-MED-968bafd9
Molecule(s):
COC1(CS(=O)(=O)N2CC(C(=O)Nc3cncc4ccccc34)c3cc(Cl)ccc3C2=O)CC1

EDJ-MED-968bafd9-1

COC1(CS(=O)(=O)N2CC(C(=O)Nc3cncc4ccccc34)c3cc(Cl)ccc3C2=O)CC1

3-aminopyridine-like Assayed Check Availability on Manifold View
COC1(CS(=O)(=O)N2CC(C(=O)Nc3cncc4cc(S(C)(=O)=O)ccc34)c3cc(Cl)ccc3C2=O)CC1

EDJ-MED-968bafd9-2

COC1(CS(=O)(=O)N2CC(C(=O)Nc3cncc4cc(S(C)(=O)=O)ccc34)c3cc(Cl)ccc3C2=O)CC1

Design Rationale:

Replacements for MAT-POS-acfe5bae-4, EDJ-MED-827e7cb4-9 based on synthetic issues and cellular potency of ALF-EVA-07677224-7

Inspired By:
Discussion:

Contributor: Ed J Griffen, MedChemica Ltd - Fri, 17 Sep 2021 16:59:07 +0000