Submission Details

EDJ-MED-70ab3faf
Molecule(s):
CC1(C(=O)Nc2cncc3ccccc23)CCS(=O)(=O)c2ccc(Cl)cc21

EDJ-MED-70ab3faf-1

CC1(C(=O)Nc2cncc3ccccc23)CCS(=O)(=O)c2ccc(Cl)cc21

3-aminopyridine-like Ordered Check Availability on Manifold View
CC1(C(=O)Nc2cncc3cc(S(C)(=O)=O)ccc23)CCS(=O)(=O)c2ccc(Cl)cc21

EDJ-MED-70ab3faf-2

CC1(C(=O)Nc2cncc3cc(S(C)(=O)=O)ccc23)CCS(=O)(=O)c2ccc(Cl)cc21

3-aminopyridine-like Ordered Check Availability on Manifold View
CN(c1ccc2c(NC(=O)C3(C)CCS(=O)(=O)c4ccc(Cl)cc43)cncc2c1)S(C)(=O)=O

EDJ-MED-70ab3faf-3

CN(c1ccc2c(NC(=O)C3(C)CCS(=O)(=O)c4ccc(Cl)cc43)cncc2c1)S(C)(=O)=O

3-aminopyridine-like Ordered Check Availability on Manifold View
Design Rationale:

P2 sulfone with quaternary Me, 7-X blocking options

Discussion:

Contributor: Ed J Griffen, MedChemica Consultancy Ltd - Fri, 29 Oct 2021 12:29:22 +0000