Submission Details

Molecule(s):
CC(=O)N1CCN(CC(=O)Nc2cnccc2C)CC1

EDJ-MED-3c65e9ce-1
Duplicate of:
BEN-DND-93268d01-8

CC(=O)N1CCN(CC(=O)Nc2cnccc2C)CC1

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
CC(=O)N1CCN(CC(=O)Nc2cnccc2C2CC2)CC1

EDJ-MED-3c65e9ce-2

CC(=O)N1CCN(CC(=O)Nc2cnccc2C2CC2)CC1

3-aminopyridine-like Assayed Check Availability on Manifold View
CC(=O)N1CCN(CC(=O)Nc2cnccc2-c2ccccc2)CC1

EDJ-MED-3c65e9ce-3

CC(=O)N1CCN(CC(=O)Nc2cnccc2-c2ccccc2)CC1

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1ccncc1NC(=O)CN1CCC(C)CC1

EDJ-MED-3c65e9ce-4

Cc1ccncc1NC(=O)CN1CCC(C)CC1

3-aminopyridine-like Assayed Check Availability on Manifold View

Design Rationale:

Addressing the attractive singleton BEN-DND-93268d01-8 with a remake and 3 close analogues to see if any potency is retained.

Discussion: