Submission Details

Molecule(s):
CS(=O)(=O)N1CC(C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2C1=O

EDJ-MED-0047eae5-1

CS(=O)(=O)N1CC(C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2C1=O

3-aminopyridine-like Check Availability on Manifold View
CN(C)S(=O)(=O)N1CC(C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2C1=O

EDJ-MED-0047eae5-2

CN(C)S(=O)(=O)N1CC(C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2C1=O

3-aminopyridine-like Check Availability on Manifold View

Design Rationale:

Learning from MIC-UNK-91acba05-3 for metabolic stability and MAT-POS-4223bc15-18 and MAT-POS-dd3ad2b5-4 for potency

Discussion: