Submission Details

Molecule(s):
O=C(Nc1cncc2ccc(F)cc12)[C@@H]1CCOc2ccc(Cl)cc21

EDG-MED-5d232de5-1

O=C(Nc1cncc2ccc(F)cc12)[C@@H]1CCOc2ccc(Cl)cc21

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Nc1cncc2ccc(F)cc12)[C@H]1CCOc2ccc(Cl)cc21

EDG-MED-5d232de5-2

O=C(Nc1cncc2ccc(F)cc12)[C@H]1CCOc2ccc(Cl)cc21

3-aminopyridine-like Assayed Check Availability on Manifold View
CC(=O)N1CC[C@@H](C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc21

EDG-MED-5d232de5-3

CC(=O)N1CC[C@@H](C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc21

3-aminopyridine-like Assayed Check Availability on Manifold View
CC(=O)N1CC[C@H](C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc21

EDG-MED-5d232de5-4

CC(=O)N1CC[C@H](C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc21

3-aminopyridine-like Assayed Check Availability on Manifold View
CN1CC[C@H](C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc21

EDG-MED-5d232de5-5

CN1CC[C@H](C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc21

3-aminopyridine-like Assayed Check Availability on Manifold View
CN1CC[C@@H](C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc21

EDG-MED-5d232de5-6

CN1CC[C@@H](C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc21

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C1[C@@H](c2cccc(Cl)c2)CCN1c1cncc2ccccc12

EDG-MED-5d232de5-7

O=C1[C@@H](c2cccc(Cl)c2)CCN1c1cncc2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C1[C@H](c2cccc(Cl)c2)CCN1c1cncc2ccccc12

EDG-MED-5d232de5-8

O=C1[C@H](c2cccc(Cl)c2)CCN1c1cncc2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View

Design Rationale:

Chiral resolution of selected compounds for further testing

Discussion: