Submission Details

Molecule(s):
O=C(CCl)N1CCN(Cc2c(Cl)cccc2Cl)CC1

DRR-IMP-38dce17f-1

O=C(CCl)N1CCN(Cc2c(Cl)cccc2Cl)CC1

O=C(CCl)N1CCN(Cc2cccc(F)c2)CC1

DRR-IMP-38dce17f-2

O=C(CCl)N1CCN(Cc2cccc(F)c2)CC1

O=C(CCl)N1CCN(Cc2ccccc2)CC1

DRR-IMP-38dce17f-3
Duplicate of:
MAK-UNK-7c9d1431-24

O=C(CCl)N1CCN(Cc2ccccc2)CC1

Duplicate piperazine-chloroacetamide Check Availability on Manifold View
N#Cc1ccc(CN2CCN(C(=O)CCl)CC2)cc1

DRR-IMP-38dce17f-7
Duplicate of:
MAK-UNK-6ca90168-14

N#Cc1ccc(CN2CCN(C(=O)CCl)CC2)cc1

Duplicate piperazine-chloroacetamide Check Availability on Manifold View
COc1cc(CN2CCN(C(=O)CCl)CC2)c([N+](=O)[O-])cc1OC

DRR-IMP-38dce17f-8

COc1cc(CN2CCN(C(=O)CCl)CC2)c([N+](=O)[O-])cc1OC


Design Rationale:

Previous sulfonamides made by MRes student (21-22). These remove the sulfonamide to give a tertiary amine

Discussion: