Submission Details

DAN-MCD-0742953f
Molecule(s):
CCOC(=O)c1cccc(NC(=O)[C@@H]2CN(C(=O)CCl)CCN2S(=O)(=O)c2ccsc2)c1

DAN-MCD-0742953f-1

CCOC(=O)c1cccc(NC(=O)[C@@H]2CN(C(=O)CCl)CCN2S(=O)(=O)c2ccsc2)c1

piperazine-chloroacetamide Assayed Check Availability on Manifold View
Design Rationale:

This compound is inspired from the one listed below. MAT-POS-ee51dedd-2 is both potent and crystallography data is available. The crystal structure of this compound is available and indicates that building from the piperazine ring could potentially link with the pocket that the 3-aminopyridine like compounds bind.

Inspired By:
Discussion:

Contributor: Dana Ferraris, McDaniel College - Fri, 20 Aug 2021 16:41:01 +0000