Submission Details
Molecule(s):
Cc1c(C#N)nc2ccc3n2c1[C@H](N[C@H](C=O)C1CC1)OC3
Design Rationale:
-13.3+/-1.3kcal in 7d1m.pdb
Other Notes:
less conformational freedom, may bind better
Cc1c(C#N)nc2ccc3n2c1[C@H](N[C@H](C=O)C1CC1)OC3
-13.3+/-1.3kcal in 7d1m.pdb
less conformational freedom, may bind better