Submission Details

CLI-TLC-36f34aa2
Molecule(s):
CN[C@H](CN1Cc2ccc(Cl)cc2[C@H](C(=O)Nc2cncc3ccccc23)C1)C(F)(F)F

CLI-TLC-36f34aa2-1

CN[C@H](CN1Cc2ccc(Cl)cc2[C@H](C(=O)Nc2cncc3ccccc23)C1)C(F)(F)F

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

amide bioisostere from J. Med. Chem. 2020, 63, 21, 12290–12358. Ligand - Protein interaction energy similar to MAT-POS-4223bc15-23 (same pose)

Inspired By:
Discussion:

Contributor: Clinton Threlfall, TLCT - Mon, 06 Sep 2021 22:06:26 +0000