Submission Details

BRU-LEF-e1854a6f

Molecule(s):

C=CC(=O)N(c1ccccn1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

BRU-LEF-e1854a6f-1

C=CC(=O)N(c1ccccn1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

Ugi Check Availability on Manifold View

Design Rationale:

Close analog of acrylamide hit LON-WEI-b8d-27. replace Ph with 2-pyridyl to modify reactivity of acrylamide

Inspired By:

CS(=O)(=O)NCCc1ccccc1

AAR-POS-d2a4d1df-1

Discussion:

Contributor: Bruce a Lefker, Lefker Biopharmaconsulting LLC - Tue, 05 May 2020 01:00:39 +0000