Submission Details

BAR-COM-ace1b61b
Molecule(s):
O=C(Nc1nncn1C1CC1)[C@@H]1CCOc2c(C3COC3)cc(Cl)cc21

BAR-COM-ace1b61b-1

O=C(Nc1nncn1C1CC1)[C@@H]1CCOc2c(C3COC3)cc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
CC(C(N)=O)c1cc(Cl)cc2c1OCC[C@H]2C(=O)Nc1nncn1C1CC1

BAR-COM-ace1b61b-2

CC(C(N)=O)c1cc(Cl)cc2c1OCC[C@H]2C(=O)Nc1nncn1C1CC1

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1nncn1C1CC1)[C@@H]1CCOc2c(OC3COC3)cc(Cl)cc21

BAR-COM-ace1b61b-3

O=C(Nc1nncn1C1CC1)[C@@H]1CCOc2c(OC3COC3)cc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
CS(=O)(=O)Nc1cc(Cl)cc2c1OCC[C@H]2C(=O)Nc1nncn1C1CC1

BAR-COM-ace1b61b-4

CS(=O)(=O)Nc1cc(Cl)cc2c1OCC[C@H]2C(=O)Nc1nncn1C1CC1

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

R groups ranked by FEP on "JAG-UCB"scaffold.

Discussion:

Contributor: Bart Lenselink, compchemist - Fri, 03 Jul 2020 18:02:29 +0000