Submission Details

Molecule(s):
COC1(c2cccc(Cl)c2)CCN(c2cncc3ccccc23)C1=O

ALP-UNI-dbb9503d-1

COC1(c2cccc(Cl)c2)CCN(c2cncc3ccccc23)C1=O

3-aminopyridine-like Assayed Check Availability on Manifold View
COC1(c2cccc(Cl)c2)CCCN(c2cncc3ccccc23)C1=O

ALP-UNI-dbb9503d-2

COC1(c2cccc(Cl)c2)CCCN(c2cncc3ccccc23)C1=O

3-aminopyridine-like Assayed Check Availability on Manifold View

Design Rationale:

Cyclise to improve metabolism, add OMe for potency.

Discussion: