Submission Details

ALP-UNI-58319883
Molecule(s):
CS(=O)(=O)NCc1ccc(Cl)cc1C1CCCN(c2cncc3ccccc23)C1=O

ALP-UNI-58319883-1

CS(=O)(=O)NCc1ccc(Cl)cc1C1CCCN(c2cncc3ccccc23)C1=O

3-aminopyridine-like Check Availability on Manifold View
O=C1C(c2cccc(Cl)c2)OCCN1c1cncc2ccccc12

ALP-UNI-58319883-2

O=C1C(c2cccc(Cl)c2)OCCN1c1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Reducing metabolism by closing the amide bond

Discussion:

Contributor: Alpha Lee, University of Cambridge - Mon, 12 Apr 2021 16:46:33 +0000