Submission Details

ALP-POS-a577c8a2
Molecule(s):
O=C(Nc1cncc2ccccc12)C1CNS(=O)(=O)c2ccc(Cl)cc21

ALP-POS-a577c8a2-1

O=C(Nc1cncc2ccccc12)C1CNS(=O)(=O)c2ccc(Cl)cc21

3-aminopyridine-like Assayed Check Availability on Manifold View
CN1CC(C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2S1(=O)=O

ALP-POS-a577c8a2-2

CN1CC(C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2S1(=O)=O

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1CN(Cc2ncc[nH]2)S(=O)(=O)c2ccc(Cl)cc21

ALP-POS-a577c8a2-3

O=C(Nc1cncc2ccccc12)C1CN(Cc2ncc[nH]2)S(=O)(=O)c2ccc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Combining the sulphone and amine designs in the P2 ring.

Discussion:

Contributor: Alpha Lee, PostEra - Sun, 02 May 2021 17:58:44 +0000