Submission Details

ALP-POS-5de921e7
Molecule(s):
COC1(C(=O)Nc2cncc(N)c2C)CCOc2ccc(Cl)cc21

ALP-POS-5de921e7-1

COC1(C(=O)Nc2cncc(N)c2C)CCOc2ccc(Cl)cc21

3-aminopyridine-like Ordered Check Availability on Manifold View
COC1(C(=O)Nc2cncc3c2CCCN3)CCOc2ccc(Cl)cc21

ALP-POS-5de921e7-2

COC1(C(=O)Nc2cncc3c2CCCN3)CCOc2ccc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
COC1(C(=O)Nc2c(C)ccnc2N)CCOc2ccc(Cl)cc21

ALP-POS-5de921e7-3

COC1(C(=O)Nc2c(C)ccnc2N)CCOc2ccc(Cl)cc21

3-aminopyridine-like Ordered Check Availability on Manifold View
COC1(C(=O)Nc2c(C)cc[nH]c2=O)CCOc2ccc(Cl)cc21

ALP-POS-5de921e7-4

COC1(C(=O)Nc2c(C)cc[nH]c2=O)CCOc2ccc(Cl)cc21

3-aminopyridine-like Ordered Check Availability on Manifold View
COC1(C(=O)Nc2cnc(N)cc2C)CCOc2ccc(Cl)cc21

ALP-POS-5de921e7-5

COC1(C(=O)Nc2cnc(N)cc2C)CCOc2ccc(Cl)cc21

3-aminopyridine-like Ordered Check Availability on Manifold View
COC1(C(=O)Nc2c[nH]c(=O)cc2C)CCOc2ccc(Cl)cc21

ALP-POS-5de921e7-6

COC1(C(=O)Nc2c[nH]c(=O)cc2C)CCOc2ccc(Cl)cc21

3-aminopyridine-like Ordered Check Availability on Manifold View
Design Rationale:

Ideas from compound prioritisation meeting with Ed Griffen and Matt Robinson.

Discussion:

Contributor: Alpha Lee, PostEra - Fri, 30 Apr 2021 14:37:20 +0000