Submission Details

ALP-POS-477dc5b7
Molecule(s):
O=C(Nc1cncc2ccccc12)C1CCCc2ccc(Cl)cc21

ALP-POS-477dc5b7-1

O=C(Nc1cncc2ccccc12)C1CCCc2ccc(Cl)cc21

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1CCNc2ccc(Cl)cc21

ALP-POS-477dc5b7-2

O=C(Nc1cncc2ccccc12)C1CCNc2ccc(Cl)cc21

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1(CCC2CC2)CCOc2ccc(Cl)cc21

ALP-POS-477dc5b7-3

O=C(Nc1cncc2ccccc12)C1(CCC2CC2)CCOc2ccc(Cl)cc21

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C1N(c2cncc3ccccc23)CCC12CCOc1ccc(Cl)cc12

ALP-POS-477dc5b7-4

O=C1N(c2cncc3ccccc23)CCC12CCOc1ccc(Cl)cc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C1N(c2cncc3ccccc23)CCCC12CCOc1ccc(Cl)cc12

ALP-POS-477dc5b7-5

O=C1N(c2cncc3ccccc23)CCCC12CCOc1ccc(Cl)cc12

3-aminopyridine-like Assayed Check Availability on Manifold View
Design Rationale:

Expanding hit by testing role of the oxygen and expanding into P1'.

Discussion:

Contributor: Alpha Lee, PostEra - Fri, 11 Sep 2020 19:01:32 +0000