Cc1nc(S(=O)(=O)N2Cc3ccc(Cl)cc3C(C(=O)Nc3cncc4ccccc34)C2)ns1
O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)c2ccc(F)s2)Cc2ccc(Cl)cc21
N#CC(F)(F)S(=O)(=O)N1Cc2ccc(Cl)cc2C(C(=O)Nc2cncc3ccccc23)C1
CC1OCCC1S(=O)(=O)N1Cc2ccc(Cl)cc2C(C(=O)Nc2cncc3ccccc23)C1
O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)c2cccnn2)Cc2ccc(Cl)cc21
O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)c2cnns2)Cc2ccc(Cl)cc21
COC1(CS(=O)(=O)N2Cc3ccc(Cl)cc3C(C(=O)Nc3cncc4ccccc34)C2)CC1
Cn1cnc(S(=O)(=O)N2Cc3ccc(Cl)cc3C(C(=O)Nc3cncc4ccccc34)C2)c1
CC1(CS(=O)(=O)N2Cc3ccc(Cl)cc3C(C(=O)Nc3cncc4ccccc34)C2)CNC1
O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)c2nnc[nH]2)Cc2ccc(Cl)cc21
Designed using Evariste's proprietary design platform, Frobenius. Utilises ligand data only, not structural information in the first instance. Model built using fluorescence IC50 data available as of 10/05/21. All based on commercially available sulfonyl chlorides (not necessarily in stock, e.g. MADE building block).